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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
16.36
Human Site:
S1754
Identified Species:
40
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
S1754
L
A
I
D
F
P
E
S
K
L
Y
W
I
S
S
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
L1775
N
Q
K
E
P
V
G
L
S
I
D
Y
V
E
N
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
Y1735
P
V
G
L
S
I
D
Y
V
E
N
K
L
Y
W
Dog
Lupus familis
XP_538245
4526
502835
S1736
L
A
I
D
F
P
E
S
K
L
Y
W
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
S1755
L
A
I
D
F
P
E
S
K
L
Y
W
I
S
S
Rat
Rattus norvegicus
P98158
4660
519258
V1924
G
N
L
Q
H
L
E
V
V
T
L
D
I
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
S1752
L
A
I
D
Y
P
E
S
K
L
Y
W
I
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
E1759
L
S
I
D
F
D
S
E
Q
L
Y
W
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
T1988
D
H
I
A
I
D
T
T
N
T
R
V
Y
F
S
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
S1740
T
G
L
A
I
D
R
S
K
Q
R
L
Y
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
0
0
100
N.A.
100
13.3
N.A.
N.A.
93.3
N.A.
66.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
33.3
13.3
100
N.A.
100
20
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
20
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
50
0
30
10
0
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
10
0
0
50
10
0
10
0
0
0
10
10
% E
% Phe:
0
0
0
0
40
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
60
0
20
10
0
0
0
10
0
0
60
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
50
0
0
10
0
0
0
% K
% Leu:
50
0
20
10
0
10
0
10
0
50
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
10
0
10
0
0
0
10
% N
% Pro:
10
0
0
0
10
40
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
10
10
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
0
% R
% Ser:
0
10
0
0
10
0
10
50
10
0
0
0
0
50
60
% S
% Thr:
10
0
0
0
0
0
10
10
0
20
0
0
0
0
10
% T
% Val:
0
10
0
0
0
10
0
10
20
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
50
0
10
10
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
50
10
20
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _